상하악에 발생한 갈색종의 증례보고
Brown tumor of the maxilla and mandible in association with primary hyperparathyroidism
이주경, 임대호, 조성대,
소속 상세정보
이주경 ( Lee Ju-Kyung ) - 전북대학교 치의학전문대학원 구강안악면외과학교실
임대호 ( Leem Dae-Ho ) - 전북대학교 치의학전문대학원 구강안악면외과학교실
조성대 ( Cho Sung-Dae ) - 전북대학교 치의학전문대학원 구강해부학교실
KMID : 0360120090310010061
Abstract
The brown tumors develop in bone and it develop on various area which in clavicle, rib bone, cervical bone, iliac bone etc. The development on the maxillofacial region is rare, relatively more develop on the mandible. The brown tumor directly develop by the dysfunction of calcium metabolism according to hyperparathyroidism and differential diagnosis with other bone lesion should be difficult if it would diagnose by only radiographic features. The histological feature is that proliferation of spindle cells with extravasated blood and haphazardly arranged, variably sized, multinucleated giant cell is seen. The brown tumor is firm diagnosed by physical examination, because of these histological feature show similar with other giant cell lesions(giant cell granuloma, aneurysmal bone cyst, cherubism) The brown tumors have been described as resulting from an imbalance of osteoclastic and osteoblastic activity. It result in bone resorption and fibrous replacement of the bone. So these lesions represent the terminal stage of hyperparathyroidism-dependent bone pathology. Therefore, it is the extremely rare finding that brown tumor in the facial bone as the first manifestation of an hyperparathyroidism. We experience 1 case of brown tumor(50 years old female) that developed on Maxilla and mandible with no history of hyperparathyroidism. So we report this case with a literature review.
키워드
Brown tumor;Primary hyperparathyroidism;Central giant cell lesion
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